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  1. Flights
  2. Chile
  3. Santiago
  4. Medellin - Santiago

Book cheap flights from Medellin to Santiago from $306

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Discover the cheapest flights from Medellin to Santiago
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Wed, 17 June
Jetsmart Airlines
Jetsmart Airlines1 stop
MDE - SCL
326$
306$
Prime price per passenger
Tue, 2 June
Jetsmart Airlines
Jetsmart AirlinesDirect
MDE - SCL
343$
336$
Prime price per passenger
Fri, 24 July
LATAM Airlines
LATAM Airlines1 stop
MDE - SCL
416$
411$
Prime price per passenger
The prices shown on this page were available within the last 20 days for the specified periods and should not be considered the final price offered. Please note that availability and prices are subject to change.

Cheapest time to fly from Medellin to Santiago

If you’re planning to fly this route soon, keep in mind that the lowest fares are usually available at the end of June. Take advantage of this per
Filter by
week: 22 June - 28 June
Flights from just $277
$319
$334
$794
$361
$306
$277
$388
$345
$355
$375
MayJuneJuly

Currency and price comparison

MealMid-priced restaurant
61%The average meal is 61% more expensive in Santiago than in Medellin.
Medellin$9.59
Santiago$15.42
TrainLocal, one-way ticket
15%Trains in Santiago are 15% cheaper than in Medellin.
Medellin$1.42
Santiago$1.23
TaxiStandard daytime start rate
247%A taxi fare in Santiago is 247% cheaper than in Medellin.
Medellin$2.15
Santiago$0.62
CoffeeRegular cappuccino
40%Coffee is 40% more expensive in Santiago than in Medellin.
Medellin$3.30
Santiago$4.62
Exchange rate
1 AUD = 650.53 CLP
1 CLP = 0 AUD
Last checked on Mon, 4/05
Distance: 4446 kms
Medellin airports
Santiago airports
Aeropuerto Comodoro Arturo Merino Benitez (SCL)How far from city centre: 15 kms

Get the Best Deals on Flights from Medellin to Santiago

Discover the best last-minute airfares and cheap prices from Medellin to Santiago with Opodo Australia. Avoid overspending on flight tickets and start planning your perfect getaway. Opodo offers a hassle-free booking experience, providing access to top airline carriers and the most competitive prices.


Find the best flights that fit your needs

When do you want to depart from Medellin? Adjust your travel dates and explore a wide range of options to Santiago. With Opodo, you can find the perfect flight from our extensive selection, ensuring a seamless and enjoyable trip. Compare prices, flight durations, and amenities to choose the best option that suits your needs.


Book all in one place

But wait, there's more! Enhance your travel experience by booking a hotel and renting a car along with your flight. It's easier and often cheaper to book everything together. Choose the best offer from Medellin to Santiago and get ready for an incredible journey. Enjoy your holiday, and remember to fasten your seatbelt. We’re ready for takeoff!

Frequently asked questions about flights from Medellin to Santiago

How long does the flight take to go from Medellin to Santiago?
The total flight time between Medellin and Santiago is of around 13 h and 35 m on average, considering an average distance of 4,446.27 km, for both direct and indirect flights for the route (which may have 1 or more stops in other cities in between).
On average, how much is the price of a flight from Medellin to Santiago?
When you fly from Medellin to Santiago the average price is $459. However, this price depends on many other factors such as seasonality or how far in advance the route has been booked.
How can I find cheap flights from Medellin to Santiago at Opodo?
The cheapest price for a flight from Medellin to Santiago is $306. At Opodo we use different machine learned based methodologies to find our costumers the best option available, considering airline combinations, stopovers and direct flights as well as different criteria for inbound and outbound journeys.
Is Santiago expensive to visit compared to Medellin?
If you compare transportation prices, the taxi ride in Santiago costs an average of $0.62, 72% cheaper than Medellin, with a fare of $2.23,
while train tickets costs 8% less in Santiago: $1.23 against $1.34 in Medellin.
If you compare the price of a lunch meal, however, you can find it from $15.44 in Santiago, 61% more than the $9.60 in Medellin.
The price of the coffee is around 54% more expensive in Santiago, with an average of $4.63 , while in Medellin the coffee costs $3.00.
Is it possible to purchase a flexible ticket for my flight from Medellin to Santiago?
At Opodo we want to make sure that your travel plans are not affected by any cancelation as well as any possible restrictions Chile may apply when travelling from Medellin. Is your flight cancelled? We've got your back! With our flexible ticket guarantee you can decide if you want to book another flight - free of rebooking fee - or get a full refund!
How is the weather in Santiago compared to Medellin?
While in Medellin temperatures can reach an average of 23º ºC in summer, Santiago's temperatures can rise to 21º ºC during the hot season. In winter, however, weather data show around 10º ºC in Santiago, compared to the 22º ºC average in Medellin.

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