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  1. Flights
  2. Ecuador
  3. Guayaquil
  4. Santiago - Guayaquil

Book cheap flights from Santiago to Guayaquil from $191

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Discover the cheapest flights from Santiago to Guayaquil
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Wed, 22 July - Wed, 29 July
LATAM Airlines
LATAM Airlines1 stop
SCL - GYE
LATAM Airlines
LATAM Airlines1 stop
GYE - SCL
428$
423$
Prime price per passenger
Wed, 22 July
LATAM Airlines
LATAM Airlines1 stop
SCL - GYE
204$
191$
Prime price per passenger
Fri, 3 July
Avianca
Avianca1 stop
SCL - GYE
323$
302$
Prime price per passenger
The prices shown on this page were available within the last 20 days for the specified periods and should not be considered the final price offered. Please note that availability and prices are subject to change.

Cheapest time to fly from Santiago to Guayaquil

If you’re planning to fly this route soon, keep in mind that the lowest fares are usually available at the beginning of August. Take advantage of this per
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week: 3 Aug - 9 Aug
Flights from just $291
$390
$628
$318
$291
$296
$300
JuneJulyAugustSeptember
Exchange rate
1 AUD = 0.71 USD
1 USD = 1.42 AUD
Last checked on Wed, 17/06
Distance: 3607 kms
Santiago airports
Aeropuerto Comodoro Arturo Merino Benitez (SCL)How far from city centre: 15 kms
Guayaquil airports

Get the Best Deals on Flights from Santiago to Guayaquil

Discover the best last-minute airfares and cheap prices from Santiago to Guayaquil with Opodo Australia. Avoid overspending on flight tickets and start planning your perfect getaway. Opodo offers a hassle-free booking experience, providing access to top airline carriers and the most competitive prices.


Find the best flights that fit your needs

When do you want to depart from Santiago? Adjust your travel dates and explore a wide range of options to Guayaquil. With Opodo, you can find the perfect flight from our extensive selection, ensuring a seamless and enjoyable trip. Compare prices, flight durations, and amenities to choose the best option that suits your needs.


Book all in one place

But wait, there's more! Enhance your travel experience by booking a hotel and renting a car along with your flight. It's easier and often cheaper to book everything together. Choose the best offer from Santiago to Guayaquil and get ready for an incredible journey. Enjoy your holiday, and remember to fasten your seatbelt. We’re ready for takeoff!

Frequently asked questions about flights from Santiago to Guayaquil

How long does the flight take to go from Santiago to Guayaquil?
The total flight time between Santiago and Guayaquil is of around 8 h and 25 m on average, considering an average distance of 3,606.64 km, for both direct and indirect flights for the route (which may have 1 or more stops in other cities in between).
On average, how much is the price of a flight from Santiago to Guayaquil?
When you fly from Santiago to Guayaquil the average price is $505. However, this price depends on many other factors such as seasonality or how far in advance the route has been booked.
How can I find cheap flights from Santiago to Guayaquil at Opodo?
The cheapest price for a flight from Santiago to Guayaquil is $191. At Opodo we use different machine learned based methodologies to find our costumers the best option available, considering airline combinations, stopovers and direct flights as well as different criteria for inbound and outbound journeys.
When is the best time to book a flight from Santiago to Guayaquil?
The most popular months to book a trip from Santiago to Guayaquil are June, February and August, based on the searches of our customers.
When is the best time to travel from Santiago to Guayaquil?
The best time of the year to go to Guayaquil when flying from Santiago depends on several preference factors like climate, seasonality and, of course, price. When it comes to popularity, October is the top 1º month to fly to Guayaquil from Santiago in terms of searches from our customer, followed by July and December. If you prefer to avoid high peaks of turism, however, and escape a crowded period, May, February and January are the months with less volume of searchs for the route Santiago - Guayaquil.
How is the weather in Guayaquil compared to Santiago?
While in Santiago temperatures can reach an average of 21º ºC in summer, Guayaquil's temperatures can rise to 28º ºC during the hot season. In winter, however, weather data show around 25º ºC in Guayaquil, compared to the 10º ºC average in Santiago.

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