FlightsHotelsFlight + HotelCars
Opodo is now available in the following countries:
Europe
PTPortugal (€)DEDeutschland (€)FRFrance (€)ESEspaña (€)UKUnited Kingdom (£)NLNederland (€)
Or you can visit ourglobal site
  1. Flights
  2. Chile
  3. Santiago
  4. Mexico City - Santiago

Book cheap flights from Mexico City to Santiago from $468

Flights
Hotels
Flight + Hotel
Car rental
Date
Date
1

Explore the best deals

Discover the cheapest flights from Mexico City to Santiago
emptyFilter
Fri, 5 June
Copa Airlines
Copa Airlines1 stop
MEX - SCL
474$
468$
Prime price per passenger
Wed, 17 June
Avianca
Avianca1 stop
MEX - SCL
495$
484$
Prime price per passenger
Wed, 8 July
Copa Airlines
Copa Airlines1 stop
MEX - SCL
523$
515$
Prime price per passenger
The prices shown on this page were available within the last 20 days for the specified periods and should not be considered the final price offered. Please note that availability and prices are subject to change.

Cheapest time to fly from Mexico City to Santiago

If you’re planning to fly this route soon, keep in mind that the lowest fares are usually available in the middle of May. Take advantage of this per
Filter by
week: 18 May - 24 May
Flights from just $446
$504
$446
$647
$613
$2,604
$608
$725
$923
$589
$1,195
$671
$560
MayJuneJuly

Currency and price comparison

MealMid-priced restaurant
3%A meal in Santiago is 3% cheaper than a meal in Mexico City.
Mexico City$15.91
Santiago$15.44
TrainLocal, one-way ticket
138%Trains are 138% more expensive in Santiago than in Mexico City.
Mexico City$0.52
Santiago$1.24
TaxiStandard daytime start rate
285%A taxi fare in Santiago is 285% cheaper than in Mexico City.
Mexico City$2.39
Santiago$0.62
CoffeeRegular cappuccino
16%Coffee in Santiago is 16% cheaper than in Mexico City.
Mexico City$5.39
Santiago$4.63
Exchange rate
1 AUD = 651.75 CLP
1 CLP = 0 AUD
Last checked on Sun, 3/05
Distance: 6613 kms
Mexico City airports
Juarez Intl Airport (MEX)How far from city centre: 6 kms
Santiago airports
Aeropuerto Comodoro Arturo Merino Benitez (SCL)How far from city centre: 15 kms

Get the Best Deals on Flights from Mexico City to Santiago

Discover the best last-minute airfares and cheap prices from Mexico City to Santiago with Opodo Australia. Avoid overspending on flight tickets and start planning your perfect getaway. Opodo offers a hassle-free booking experience, providing access to top airline carriers and the most competitive prices.


Find the best flights that fit your needs

When do you want to depart from Mexico City? Adjust your travel dates and explore a wide range of options to Santiago. With Opodo, you can find the perfect flight from our extensive selection, ensuring a seamless and enjoyable trip. Compare prices, flight durations, and amenities to choose the best option that suits your needs.


Book all in one place

But wait, there's more! Enhance your travel experience by booking a hotel and renting a car along with your flight. It's easier and often cheaper to book everything together. Choose the best offer from Mexico City to Santiago and get ready for an incredible journey. Enjoy your holiday, and remember to fasten your seatbelt. We’re ready for takeoff!

Frequently asked questions about flights from Mexico City to Santiago

How long does the flight take to go from Mexico City to Santiago?
The total flight time between Mexico City and Santiago is of around 10 h and 15 m on average, considering an average distance of 6,612.64 km, for both direct and indirect flights for the route (which may have 1 or more stops in other cities in between).
On average, how much is the price of a flight from Mexico City to Santiago?
When you fly from Mexico City to Santiago the average price is $783. However, this price depends on many other factors such as seasonality or how far in advance the route has been booked.
How can I find cheap flights from Mexico City to Santiago at Opodo?
The cheapest price for a flight from Mexico City to Santiago is $468. At Opodo we use different machine learned based methodologies to find our costumers the best option available, considering airline combinations, stopovers and direct flights as well as different criteria for inbound and outbound journeys.
Is Santiago expensive to visit compared to Mexico City?
If you compare transportation prices, the taxi ride in Santiago costs an average of $0.62, 74% cheaper than Mexico City, with a fare of $2.39,
while train tickets costs 120% more in Santiago: $1.23 against $0.56 in Mexico City.
If you compare the price of a lunch meal, however, you can find it from $15.42 in Santiago, 3% less than the $15.91 in Mexico City.
The price of the coffee is around 14% cheaper in Santiago, with an average of $4.62, while in Mexico City the coffee costs $5.39.
Is it possible to purchase a flexible ticket for my flight from Mexico City to Santiago?
At Opodo we want to make sure that your travel plans are not affected by any cancelation as well as any possible restrictions Chile may apply when travelling from Mexico City. Is your flight cancelled? We've got your back! With our flexible ticket guarantee you can decide if you want to book another flight - free of rebooking fee - or get a full refund!
How is the weather in Santiago compared to Mexico City?
While in Mexico City temperatures can reach an average of 18º ºC in summer, Santiago's temperatures can rise to 21º ºC during the hot season. In winter, however, weather data show around 10º ºC in Santiago, compared to the 14º ºC average in Mexico City.

Plan your trip

Popular Flight RoutesOther popular routes to explore